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Human NGF- Beta

Recombinant Active Protein
Cat. No. 
600161
Unit 
0.02 mg
Price $250.00

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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description 
Human NGF-beta is a neurotrophic factor related to BDNF, NT-3 and NT-4. Human NGF-beta acts as a  neurotrophic factor through its receptor beta-NGFR. This cytokine stimulates division and differentiation of sympathetic and embryonic sensory neurons, and is also involved in the growth and differentiation of B lymphocytes and B-cell survival. Human NGF-beta is a noncovalently disulfide-linked homodimer consisting of 121 amino acids with a MW of 2 x 13.6 kDa.

Spec Container

Datasheet
Format 
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Alternate Names 
Beta-Nerve growth factor; Beta NGF; NGF; NGFB
Accession No.  
P01138
MW 
13600 Da
Sequence 
MSSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRR
Source 
E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Purity 
Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by RP-HPLC calibrated against a known standard and quantitation on SDS-PAGE against a known standard.
Application Notes 
Biological activity is determined by the ability to stimulate neurite growth in chick E9 DRG cells. The ED50 is < 1.0 ng/ml.
Storage 
Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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For research use only, not for diagnostic or therapeutic procedures.