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I have a slight fascination with sweeteners. About five years ago I imported a kilo of "Neotame" sweetener from a chem factory in Shanghai. It was claimed to be 10,000-12,000 times sweeter than sugar. It's a white powder and came in a metal can with a crimped lid and typically plain chemical labeling. Supposedly it is FDA-approved and a distant derivative of aspartame.

US customs held it for two weeks before sending it on to Colorado with no explanation. When received, the box was covered in "inspected" tape and they had put the canister in a clear plastic bag. The crimped lid looked like a rottweiler chewed it open and white powder was all over the inside of the bag. I unwisely opened this in my kitchen with no respirator as advised by the MSDS which I read after the fact (I am not a smart man).

Despite careful handling of the bag, it is so fine in composition that a small cloud of powder erupted in front of me and a hazy layer of the stuff settled over the kitchen. Eyes burning and some mild choking from inhaling the cloud, I instantly marveled at how unbelievably sweet the air tasted, and it was delicious. For several hours I could still taste it on my lips. The poor customs inspector will have had a lasting memory of that container I'm pretty sure.

Even after a thorough wipe-down, to this day I encounter items in my kitchen with visually imperceptible amounts of residue. After touching it and getting even microscopic quantities of the stuff on a utensil or cup, bowl, plate, whatever, it adds an intense element of sweetness to the food being prepared, sometimes to our delight. I still have more than 900g even after giving away multiple baggies to friends and family (with proper safety precautions).

We have been hooked on it since that first encounter. I keep a 100mL bottle of solution in the fridge which is used to fill smaller dropper bottles. I've prepared that 100mL bottle three times over five years, and that works out to about 12g of personal (somewhat heavy) usage for two people in that time. Probably nowhere near the LD50.

I carry a tiny 30mL dropper bottle of the solution for sweetening the nasty office coffee and anything else as appropriate. Four drops to a normal cup of coffee. We sweeten home-carbonated beverages, oatmeal, baked goods (it is heat stable), use it in marinades, and countless other applications.

I don't know if it's safe. The actual quantity used is so incredibly tiny that it seems irrelevant. I'd sweeten my coffee with polonium-210 if it could be done in Neotame-like quantities. Between this, a salt shaker loaded with MSG and a Darwin fish on my car, I'm doomed anyway.




Just wanted to say this comment made me wish there was a way to nominate comments for a "best of HN" section :)

Also: http://www.ebay.com/itm/0-Calorie-Pure-Newtame-powder-10-tim... ships from San Diego if anyone is looking to replicate OP.


Interestingly, from the Wikipedia page:

> The patent covering the neotame molecule in the US, 5,480,668,[10] was originally set to expire 7 November 2012, but was extended 973 days by the U.S. Patent and Trademark Office. The patent is now set to expire 8 July 2015.

Give Animats comment below about how Sucralose is being manufactured more now that its patent has expired it will be interesting to see what happens once Neotame's patent expires later this year.




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