newsletter/2015/11 (Link Bibliography)

“newsletter/​2015/​11” links:

  1. https://gwern.substack.com

  2. 10

  3. Changelog

  4. https://www.patreon.com/gwern

  5. 2016-smith.pdf: ⁠, D J. Smith, V. Escott-Price, G. Davies, M. E S. Bailey, L. Colodro-Conde, J. Ward, A. Vedernikov, R. Marioni, B. Cullen, D. Lyall, S. P Hagenaars, D. C M. Liewald, M. Luciano, C. R Gale, S. J Ritchie, C. Hayward, B. Nicholl, B. Bulik-Sullivan, M. Adams, B. Couvy-Duchesne, N. Graham, D. Mackay, J. Evans, B. H Smith, D. J Porteous, S. E Medland, N. G Martin, P. Holmans, A. M McIntosh, J. P Pell, I. J Deary, M. C O'Donovan (2016-01-01; genetics  /​ ​​ ​correlation):

    Neuroticism is a personality trait of fundamental importance for psychological well-being and public health. It is strongly associated with major depressive disorder (MDD) and several other psychiatric conditions. Although neuroticism is heritable, attempts to identify the alleles involved in previous studies have been limited by relatively small sample sizes. Here we report a combined of (GWAS) of neuroticism that includes 91 370 participants from the UK Biobank cohort, 6659 participants from the Generation Scotland: Scottish Family Health Study (GS:SFHS) and 8687 participants from a QIMR (Queensland Institute of Medical Research) Berghofer Medical Research Institute (QIMR) cohort. All participants were assessed using the same neuroticism instrument, the Personality Questionnaire-Revised (EPQ-R-S) Short Form’s scale. We found a -based heritability estimate for neuroticism of ~15% (s.e. = 0.7%). Meta-analysis identified nine novel loci associated with neuroticism. The strongest evidence for association was at a locus on chromosome 8 (P = 1.5 × 10−15) spanning 4 Mb and containing at least 36 genes. Other associated loci included interesting candidate genes on chromosome 1 (GRIK3 (glutamate receptor ionotropic kainate 3)), chromosome 4 (KLHL2 (Kelch-like protein 2)), chromosome 17 (CRHR1 (corticotropin-releasing hormone receptor 1) and MAPT (microtubule-associated protein Tau)) and on chromosome 18 (CELF4 (CUGBP elav-like family member 4)). We found no evidence for genetic differences in the common allelic architecture of neuroticism by sex. By comparing our findings with those of the Psychiatric Genetics Consortia, we identified a strong between neuroticism and MDD and a less strong but genetic correlation with schizophrenia, although not with bipolar disorder. Polygenic risk scores derived from the primary sample captured ~1% of the in neuroticism in the GS:SFHS and QIMR samples, although most of the genome-wide statistically-significant alleles identified within a UK Biobank-only GWAS of neuroticism were not independently replicated within these cohorts. The identification of nine novel neuroticism-associated loci will drive forward future work on the neurobiology of neuroticism and related phenotypes.

  6. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.422.4232&rep=rep1&type=pdf

  7. http://drjamesthompson.blogspot.com/2015/11/genetic-story-jumps-ahead.html

  8. 2015-krapohl.pdf

  9. 2015-mathieson.pdf: “Genome-wide patterns of selection in 230 ancient Eurasians”⁠, Iosif Lazaridis, Nadin Rohland, Swapan Mallick, Nick Patterson, Songül Alpaslan Roodenberg, Eadaoin Harney, Kristin Stewardson, Daniel Fernandes, Mario Novak, Kendra Sirak, Cristina Gamba, Eppie R. Jones, Bastien Llamas, Stanislav Dryomov, Joseph Pickrell, Juan Luís Arsuaga, José María Bermúdez de Castro, Eudald Carbonell, Fokke Gerritsen, Aleksandr Khokhlov, Pavel Kuznetsov, Marina Lozano, Harald Meller, Oleg Mochalov, Vyacheslav Moiseyev, Manuel A. Rojo Guerra, Jacob Roodenberg, Josep Maria Vergès, Johannes Krause, Alan Cooper, Kurt W. Alt, Dorcas Brown, David Anthony, Carles Lalueza-Fox, Iain Mathieson, Wolfgang Haak, Ron Pinhasi, David Reich

  10. https://www.nytimes.com/2015/11/24/science/agriculture-linked-to-dna-changes-in-ancient-europe.html

  11. https://www.atlasobscura.com/articles/in-the-early-1900s-dozens-of-centuriesold-european-buildings-came-to-america-where-is-medieval-america-now

  12. 2012-11-13-yvain-bookreviewempireofthesummermoon.html

  13. https://www.nytimes.com/2012/11/08/us/politics/little-to-show-for-cash-flood-by-big-donors.html?pagewanted=all

  14. https://www.lesswrong.com/posts/7FzD7pNm9X68Gp5ZC/why-our-kind-can-t-cooperate

  15. index.html

  16. 2011-nationalpost-stoningguidelines.pdf

  17. http://joshmitteldorf.scienceblog.com/2012/11/10/mortality-and-life-expectancy/

  18. http://flowingdata.com/2010/08/31/how-to-visualize-data-with-cartoonish-faces/

  19. https://www.nytimes.com/2012/11/18/magazine/ashlyn-blocker-feels-no-pain.html?pagewanted=all

  20. http://blog.givewell.org/2012/11/09/insecticide-resistance-and-malaria-control/

  21. https://docs.google.com/spreadsheets/d/19D8JUgf95t-f-oUAHqh8Nn2G90KO3gUiua9yAjBSSqI/edit

  22. 1976-hill.pdf

  23. ⁠, Nagendra, Ravindra P. Maruthai, Nirmala Kutty, Bindu M (2012):

    Intense meditation practices help to achieve a harmony between body and mind. Meditation practices influence brain functions, induce various intrinsic neural plasticity events, modulate autonomic, metabolic, endocrine, and immune functions and thus mediate global regulatory changes in various behavioral states including sleep. This brief review focuses on the effect of meditation as a self regulatory phenomenon on sleep.

  24. http://www.wired.com/2015/11/carnegie-mellon-denies-fbi-paid-for-tor-breaking-research/

  25. https://bitslog.wordpress.com/2015/09/11/dagcoin/

  26. http://hackingdistributed.com/2015/10/14/bitcoin-ng/

  27. https://old.reddit.com/r/afinil/comments/3sgb9o/air_force_cadet_sentenced_to_3_years_after_buying/

  28. https://bugs.debian.org/cgi-bin/bugreport.cgi?bug=641166

  29. https://www.nytimes.com/2012/11/19/science/earth/as-coasts-rebuild-and-us-pays-again-critics-stop-to-ask-why.html?hp&pagewanted=all

  30. http://www.popularmechanics.com/science/energy/a8273/should-the-northeast-bury-its-power-lines-to-prevent-outages-14295683/

  31. http://johnhcochrane.blogspot.com/2012/11/debt-maturity.html

  32. http://web.mit.edu/krugman/www/ricardo.htm

  33. http://www.theglobalist.com/the-real-winners-and-losers-of-globalization/

  34. http://boingboing.net/2011/02/03/cosmic-commodities-h.html

  35. http://cheaptalk.org/2012/11/04/the-goethe-auction/

  36. http://mason.gmu.edu/~rhanson/extraord.pdf

  37. https://plato.stanford.edu/entries/humor/

  38. http://www.stevepetersen.net/wittgenstein-fog.html

  39. http://www.asofterworld.com/index.php?id=891

  40. http://thecodelesscode.com/case/66

  41. Books#a-perfect-vacuum-lem-1999

  42. https://www.amazon.com/Do-No-Harm-Stories-Surgery/dp/125006581X

  43. Statistical-notes#operating-on-an-aneurysm

  44. https://www.amazon.com/Digital-Gold-Bitcoin-Millionaires-Reinvent/dp/0062362496

  45. Books#digital-gold-popper-2015

  46. http://ajjacobs.com/books/drop-dead-healthy/

  47. Books#drop-dead-healthy-jacobs-2012

  48. https://www.youtube.com/watch?v=QZBDA8nw200

  49. https://www.youtube.com/d3NYFVPvsbw?t=11m12s

  50. https://www.dropbox.com/s/z4kgzznsfp1ow91/%E6%BC%89%E9%A4%A1-%E6%B0%B4%E5%8F%A4%E8%AD%9Asuikotan-littlebravery.ogg

  51. https://www.dropbox.com/s/szlh8yrb1vzyvcn/%E6%BC%89%E9%A4%A1-%E6%B0%B4%E5%8F%A4%E8%AD%9Asuikotan-%E8%92%BC%E6%9C%88%E5%A4%9Cinstrumental.ogg

  52. https://www.dropbox.com/s/7zr44yzub3o8286/%E6%B0%B4%E6%A9%8B%E3%82%86%E3%81%A3%E3%81%8D-teahakugyokurou-%E5%A4%95%E6%9A%AE%E3%82%8C%E8%89%B2%E3%81%AE%E3%82%AB%E3%83%83%E3%83%97.ogg

  53. https://www.youtube.com/watch?v=_-qqIaeYrIM

  54. https://endolphinrecords.bandcamp.com/track/--12

  55. https://www.dropbox.com/s/g5d1d29f69lbjs5/cyostyle-cy-youagainmylove.ogg

  56. https://www.youtube.com/watch?v=MFSj0PjAI9k

  57. https://www.dropbox.com/s/z4trtsf4xyyrrpv/atols-atolsmiku0-newyearslong.ogg

  58. https://www.youtube.com/watch?v=ExjhUALdntM