- See Also
-
Links
- “Functional and Multi-Omic Aging Rejuvenation With GLP-1R Agonism”, Huang et al 2024
- “Epigenetic Age Oscillates during the Day”, Koncevičius et al 2024
- “A Lipidome Aging Clock Shows Age Acceleration in Individuals With Autism”, Latumalea et al 2024
- “A Universal Molecular Mechanism Driving Aging”, Jin et al 2024
- “Mechanisms, Pathways and Strategies for Rejuvenation through Epigenetic Reprogramming”, Cipriano et al 2023
- “Calorie Restriction Modulates the Transcription of Genes Related to Stress Response and Longevity in Human Muscle: The CALERIE Study”, Das et al 2023
- “Multi-Omic Rejuvenation and Life Span Extension on Exposure to Youthful Circulation [parabiosis]”, Zhang et al 2023b
- “Reprogramming by Drug-Like Molecules Leads to Regeneration of Cochlear Hair Cell-Like Cells in Adult Mice”, Quan et al 2023
- “Epigenetic Fidelity in Complex Biological Systems and Implications for Ageing”, Duffield et al 2023
- “Centenarian Clocks: Epigenetic Clocks for Validating Claims of Exceptional Longevity”, Dec et al 2023
- “Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice”, Macip et al 2023
- “Longevity and Rejuvenation Effects of Cell Reprogramming Are Decoupled from Loss of Somatic Identity”, Kriukov et al 2022
- “A Generalizable Epigenetic Clock Captures Aging in Two Nonhuman Primates”, Goldman et al 2022
- “Aging Clocks, Entropy, and the Limits of Age-Reversal”, Tarkhov et al 2022
- “Centenarians Consistently Present a Younger Epigenetic Age Than Their Chronological Age With 4 Epigenetic Clocks Based on a Small Number of CpG Sites”, Daunay et al 2022
- “Chemical Reprogramming Ameliorates Cellular Hallmarks of Aging and Extends Lifespan”, Schoenfeldt et al 2022
- “In Vivo Reprogramming Leads to Premature Death due to Hepatic and Intestinal Failure.”, Parras et al 2022
- “DNA Methylation Clocks for Dogs and Humans”, Horvath et al 2022
- “Making Sense of the Ageing Methylome”, Seale et al 2022
- “In Vivo Partial Reprogramming Alters Age-Associated Molecular Changes during Physiological Aging in Mice”, Browder et al 2022
- “Clock Work: Deconstructing the Epigenetic Clock Signals in Aging, Disease, and Reprogramming”, Levine et al 2022
- “An Open Science Study of Ageing in Companion Dogs”, Creevy et al 2022
- “Heterochronic Parabiosis Reprograms the Mouse Brain Transcriptome by Shifting Aging Signatures in Multiple Cell Types”, Ximerakis et al 2022
- “Multi-Omic Rejuvenation of Naturally Aged Tissues by a Single Cycle of Transient Reprogramming”, Chondronasiou et al 2022
- “An Epigenetic Aging Analysis of Randomized Metformin and Weight Loss Interventions in Overweight Postmenopausal Breast Cancer Survivors”, Nwanaji-Enwerem et al 2021
- “Profiling Epigenetic Age in Single Cells”, Trapp et al 2021
- “Rejuvant®, a Potential Life-Extending Compound Formulation With Alpha-Ketoglutarate and Vitamins, Conferred an Average 8 Year Reduction in Biological Aging, After an Average of 7 Months of Use, in the TruAge DNA Methylation Test”, Demidenko1 et al 2021
- “Nutritional Reprogramming of Mouse Liver Proteome Is Dampened by Metformin, Resveratrol, and Rapamycin”, Couteur et al 2021
- “Ultra-Cheap and Scalable Epigenetic Age Predictions With TIME-Seq”, Griffin et al 2021
- “Many Chronological Aging Clocks Can Be Found throughout the Epigenome: Implications for Quantifying Biological Aging”, Porter et al 2021
- “Genome-Wide Methylation Data Improves Dissection of the Effect of Smoking on Body Mass Index”, Amador et al 2021
- “Partial Reprogramming Restores Youthful Gene Expression through Transient Suppression of Cell Identity”, Roux et al 2021
- “Epigenetic Predictors of Maximum Lifespan and Other Life History Traits in Mammals”, Li et al 2021
- “Universal DNA Methylation Age across Mammalian Tissues”, Consortium et al 2021
- “Reprogramming to Recover Youthful Epigenetic Information and Restore Vision”, Lu et al 2020
- “Sight Restored by Turning Back the Epigenetic Clock: Neurons Progressively Deteriorate With Age and Lose Resilience to Injury. It Emerges That Treatment With Three Transcription Factors Can Re-Endow Neurons in the Mature Eye With Youthful Characteristics and the Capacity to Regenerate.”, Huberman 2020
- “Reversal of Epigenetic Age With Diet and Lifestyle in a Pilot Randomized Clinical Trial”, Fitzgerald et al 2020
- “Epigenetic Clocks: A Review”, Luis 2020
- “Reversal of Aging via in Vivo Epigenetic Reprogramming”, Lu 2020b
- “Current Perspectives on the Cellular and Molecular Features of Epigenetic Ageing”, Raj & Horvath 2020
- “Erosion of the Epigenetic Landscape and Loss of Cellular Identity As a Cause of Aging in Mammals”, Yang et al 2019
- “TRIIM: Reversal of Epigenetic Aging and Immunosenescent Trends in Humans”, Fahy et al 2019
- “DNA Methylation GrimAge Strongly Predicts Lifespan and Healthspan”, Lu et al 2019
- “Epigenetic Prediction of Complex Traits and Death”, McCartney et al 2018
- “DNAm PhenoAge: An Epigenetic Biomarker of Aging for Lifespan and Healthspan”, Levine et al 2018
- “Too Much Success for Recent Groundbreaking Epigenetic Experiments”, Francis 2014
- “Large Offspring Syndrome: a Bovine Model for the Human Loss-Of-Imprinting Overgrowth Syndrome Beckwith-Wiedemann”, Chen et al 2013
- “DNA Methylation Age of Human Tissues and Cell Types”, Horvath 2013
- “Morphological Abnormalities, Impaired Fetal Development and Decrease in Myostatin Expression following Somatic Cell Nuclear Transfer in Dogs”, Hong et al 2011
- Wikipedia
- Miscellaneous
- Link Bibliography
See Also
Links
“Functional and Multi-Omic Aging Rejuvenation With GLP-1R Agonism”, Huang et al 2024
Functional and multi-omic aging rejuvenation with GLP-1R agonism
“Epigenetic Age Oscillates during the Day”, Koncevičius et al 2024
“A Lipidome Aging Clock Shows Age Acceleration in Individuals With Autism”, Latumalea et al 2024
A lipidome Aging Clock shows Age Acceleration in individuals with Autism
“A Universal Molecular Mechanism Driving Aging”, Jin et al 2024
“Mechanisms, Pathways and Strategies for Rejuvenation through Epigenetic Reprogramming”, Cipriano et al 2023
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming
“Calorie Restriction Modulates the Transcription of Genes Related to Stress Response and Longevity in Human Muscle: The CALERIE Study”, Das et al 2023
“Multi-Omic Rejuvenation and Life Span Extension on Exposure to Youthful Circulation [parabiosis]”, Zhang et al 2023b
Multi-omic rejuvenation and life span extension on exposure to youthful circulation [parabiosis]
“Reprogramming by Drug-Like Molecules Leads to Regeneration of Cochlear Hair Cell-Like Cells in Adult Mice”, Quan et al 2023
“Epigenetic Fidelity in Complex Biological Systems and Implications for Ageing”, Duffield et al 2023
Epigenetic fidelity in complex biological systems and implications for ageing
“Centenarian Clocks: Epigenetic Clocks for Validating Claims of Exceptional Longevity”, Dec et al 2023
Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity
“Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice”, Macip et al 2023
“Longevity and Rejuvenation Effects of Cell Reprogramming Are Decoupled from Loss of Somatic Identity”, Kriukov et al 2022
Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity
“A Generalizable Epigenetic Clock Captures Aging in Two Nonhuman Primates”, Goldman et al 2022
A generalizable epigenetic clock captures aging in two nonhuman primates
“Aging Clocks, Entropy, and the Limits of Age-Reversal”, Tarkhov et al 2022
“Centenarians Consistently Present a Younger Epigenetic Age Than Their Chronological Age With 4 Epigenetic Clocks Based on a Small Number of CpG Sites”, Daunay et al 2022
“Chemical Reprogramming Ameliorates Cellular Hallmarks of Aging and Extends Lifespan”, Schoenfeldt et al 2022
Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan
“In Vivo Reprogramming Leads to Premature Death due to Hepatic and Intestinal Failure.”, Parras et al 2022
In vivo reprogramming leads to premature death due to hepatic and intestinal failure.
“DNA Methylation Clocks for Dogs and Humans”, Horvath et al 2022
“Making Sense of the Ageing Methylome”, Seale et al 2022
“In Vivo Partial Reprogramming Alters Age-Associated Molecular Changes during Physiological Aging in Mice”, Browder et al 2022
“Clock Work: Deconstructing the Epigenetic Clock Signals in Aging, Disease, and Reprogramming”, Levine et al 2022
Clock Work: Deconstructing the Epigenetic Clock Signals in Aging, Disease, and Reprogramming
“An Open Science Study of Ageing in Companion Dogs”, Creevy et al 2022
“Heterochronic Parabiosis Reprograms the Mouse Brain Transcriptome by Shifting Aging Signatures in Multiple Cell Types”, Ximerakis et al 2022
“Multi-Omic Rejuvenation of Naturally Aged Tissues by a Single Cycle of Transient Reprogramming”, Chondronasiou et al 2022
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
“An Epigenetic Aging Analysis of Randomized Metformin and Weight Loss Interventions in Overweight Postmenopausal Breast Cancer Survivors”, Nwanaji-Enwerem et al 2021
“Profiling Epigenetic Age in Single Cells”, Trapp et al 2021
“Rejuvant®, a Potential Life-Extending Compound Formulation With Alpha-Ketoglutarate and Vitamins, Conferred an Average 8 Year Reduction in Biological Aging, After an Average of 7 Months of Use, in the TruAge DNA Methylation Test”, Demidenko1 et al 2021
“Nutritional Reprogramming of Mouse Liver Proteome Is Dampened by Metformin, Resveratrol, and Rapamycin”, Couteur et al 2021
“Ultra-Cheap and Scalable Epigenetic Age Predictions With TIME-Seq”, Griffin et al 2021
Ultra-cheap and scalable epigenetic age predictions with TIME-Seq
“Many Chronological Aging Clocks Can Be Found throughout the Epigenome: Implications for Quantifying Biological Aging”, Porter et al 2021
“Genome-Wide Methylation Data Improves Dissection of the Effect of Smoking on Body Mass Index”, Amador et al 2021
Genome-wide methylation data improves dissection of the effect of smoking on body mass index
“Partial Reprogramming Restores Youthful Gene Expression through Transient Suppression of Cell Identity”, Roux et al 2021
“Epigenetic Predictors of Maximum Lifespan and Other Life History Traits in Mammals”, Li et al 2021
Epigenetic predictors of maximum lifespan and other life history traits in mammals
“Universal DNA Methylation Age across Mammalian Tissues”, Consortium et al 2021
“Reprogramming to Recover Youthful Epigenetic Information and Restore Vision”, Lu et al 2020
Reprogramming to recover youthful epigenetic information and restore vision
“Sight Restored by Turning Back the Epigenetic Clock: Neurons Progressively Deteriorate With Age and Lose Resilience to Injury. It Emerges That Treatment With Three Transcription Factors Can Re-Endow Neurons in the Mature Eye With Youthful Characteristics and the Capacity to Regenerate.”, Huberman 2020
“Reversal of Epigenetic Age With Diet and Lifestyle in a Pilot Randomized Clinical Trial”, Fitzgerald et al 2020
Reversal of Epigenetic Age with Diet and Lifestyle in a Pilot Randomized Clinical Trial
“Epigenetic Clocks: A Review”, Luis 2020
“Reversal of Aging via in Vivo Epigenetic Reprogramming”, Lu 2020b
“Current Perspectives on the Cellular and Molecular Features of Epigenetic Ageing”, Raj & Horvath 2020
Current perspectives on the cellular and molecular features of epigenetic ageing
“Erosion of the Epigenetic Landscape and Loss of Cellular Identity As a Cause of Aging in Mammals”, Yang et al 2019
Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals
“TRIIM: Reversal of Epigenetic Aging and Immunosenescent Trends in Humans”, Fahy et al 2019
TRIIM: Reversal of epigenetic aging and immunosenescent trends in humans
“DNA Methylation GrimAge Strongly Predicts Lifespan and Healthspan”, Lu et al 2019
DNA methylation GrimAge strongly predicts lifespan and healthspan
“Epigenetic Prediction of Complex Traits and Death”, McCartney et al 2018
“DNAm PhenoAge: An Epigenetic Biomarker of Aging for Lifespan and Healthspan”, Levine et al 2018
DNAm PhenoAge: An epigenetic biomarker of aging for lifespan and healthspan
“Too Much Success for Recent Groundbreaking Epigenetic Experiments”, Francis 2014
Too much success for recent groundbreaking epigenetic experiments
“Large Offspring Syndrome: a Bovine Model for the Human Loss-Of-Imprinting Overgrowth Syndrome Beckwith-Wiedemann”, Chen et al 2013
“DNA Methylation Age of Human Tissues and Cell Types”, Horvath 2013
“Morphological Abnormalities, Impaired Fetal Development and Decrease in Myostatin Expression following Somatic Cell Nuclear Transfer in Dogs”, Hong et al 2011
Wikipedia
Miscellaneous
-
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1824-y -
https://razib.substack.com/p/you-cant-take-it-with-you-straight -
https://www.nytimes.com/2023/08/10/science/wildlife-aging-epigenetic-clocks.html -
https://www.sens.org/wouldnt-cellular-reprogramming-be-enough/: -
https://www.theguardian.com/science/2022/jun/13/biological-age-startups-why
Link Bibliography
-
2023-zhang-2.pdf: “Multi-Omic Rejuvenation and Life Span Extension on Exposure to Youthful Circulation [parabiosis]”, -
https://www.biorxiv.org/content/10.1101/2023.01.04.522507.full: “Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice”, -
https://www.aging-us.com/article/204316/text: “Centenarians Consistently Present a Younger Epigenetic Age Than Their Chronological Age With 4 Epigenetic Clocks Based on a Small Number of CpG Sites”, -
https://www.pnas.org/doi/full/10.1073/pnas.2120887119: “DNA Methylation Clocks for Dogs and Humans”, -
2022-browder.pdf: “In Vivo Partial Reprogramming Alters Age-Associated Molecular Changes during Physiological Aging in Mice”, -
2022-creevy.pdf: “An Open Science Study of Ageing in Companion Dogs”, -
https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-021-01218-y: “An Epigenetic Aging Analysis of Randomized Metformin and Weight Loss Interventions in Overweight Postmenopausal Breast Cancer Survivors”, -
2021-trapp.pdf: “Profiling Epigenetic Age in Single Cells”, -
https://nintil.com/epigenetic-clocks: “Epigenetic Clocks: A Review”,